Researchers at Huntsman Cancer Institute (HCI) at the
During both normal and cancerous cell growth, a cellular process takes place that involves both glucose (sugar) and glutamine (an amino acid). Glucose and glutamine are both essential for cell growth and thought to operate independently.
However, research conducted under Don Ayer, Ph.D., a Huntsman Cancer Institute investigator and professor in the Department of Oncological Sciences at the
He discovered that by restricting glutamine availability, glucose utilization is also stopped. This finding could lead to new drugs that would target glutamine utilization, or target MondoA or TXNIP.